Current Perspectives: Therapeutic Uses of Tobramycin

Perspectives on the Potential Therapeutic Uses of Vesicles

The role of extracellular vesicles as an important mediator of cell-to-cell communication has been well established by many studies that have shown their capability for exchanging proteins, bioactive lipids and nucleic acids. Extracellular vesicles have been implicated in several physiological and pathological processes according to the cell of origin. Identification of the innate properties of...

Alzheimer's disease: current and future therapeutic perspectives.

1. A better understanding of the pathophysiology of AD has been made possible through population-based epidemiological studies, human genetic and post-mortem studies, leading to a number of testable hypothesis towards delaying progression. 2. A number of disease milestones have been identified as therapeutic targets, such as conversion from MCI to diagnosable dementia. 3. Clinicians caring for ...

Thalidomide: current therapeutic uses and management of its toxicities.

Thalidomide currently is used to treat relapsed and refractory multiple myeloma. The drug also is being actively investigated in patients newly diagnosed with multiple myeloma. The therapeutic applications of thalidomide are expected to grow as clinical trials document its activity in treating other neoplastic disorders and diseases. Healthcare providers need to be well informed of its toxiciti...

Solanum nigrum: current perspectives on therapeutic properties.

Therapeutic Uses of Exosomes

Exosomes are membrane vesicles with a diameter of 40-100 nm that are secreted by many cell types into the extracel‐ lular milieu. Exosomes are found in cell culture superna‐ tants and in different biological fluids and are known to be secreted by most cell types under normal and pathological conditions. Considerable research is focusing on the exploitation of exosomes in biological fluids for b...